Synthetic cannabinoids, also known commonly known by the name of k2 Spice, first became available in the U.S. in the mid-2000’s. These synthetic products are designer drugs in which incense or other leafy materials are sprayed with lab-synthesized liquid chemicals to mimic (copy) the effect of THC, the psychoactive ingredient in the naturally grown cannabis sativa plant.
Synthetic cannabinoids are sometimes incorrectly called synthetic weeds, and they are often promoted as safe or legal substitutes to natural marijuana. There is no actual marijuana plant in synthetic cannabinoids; however, the action of the chemicals still take affect on the cannabinoid receptors in the brain. Synthetic cannabinoids can produce very different actions from smoking natural marijuana. The effects can be much more intense, unpleasant and sometimes dangerous compared to naturally-grown marijuana.
Who’s Using k2 spice?
Unfortunately, as an inexpensive and easy-to-obtain drug, synthetic marijuana has is used among wide-ranging demographics. Billed as a “safe” alternative to marijuana that standard drug tests can’t detect, even high school athletes are turning to K2. The same goes for young workers who are subject to random drug testing. The results are devastating among every group: K2 leads to lasting lung damage, heart damage, coma and even death. As three users shared with PBS, these effects can occur after a single use.
What chemicals are in Spice or K2?
The cannabinoid compounds found in these synthetic agents act on the same cell receptors as those affected by the THC in natural marijuana. Identified compounds include2:
HU-210
CP 47,497 and homologues
JWH-018
JWH-073
JWH-398
JWH-250
oleamide
Some of the synthesized compounds in synthetic cannabinoids bind much more strongly to THC receptors than regular marijuana, which can lead to more powerful, unpredictable or dangerous effects. Some synthesized compounds have been noted to be 100 times more potent than the average THC found in marijuana. The stronger binding of the synthetic chemicals to the THC receptor sites in the brain may lead to the extreme anxiety and paranoia that have been reported in some users.
Use of synthetic cannabinoids is alarmingly high, especially among young people. According to the 2012 Monitoring the Future survey of youth drug-use trends, one in nine 12th graders in America reported using synthetic cannabinoids in the past year. This rate, unchanged from 2011, puts synthetic cannabinoids as the second most frequently used illegal drug among high school seniors after marijuana (see chart).
Synthetic cathinones are man-made chemicals related to amphetamines. Synthetic cathinone products often consist of methylenedioxypyrovalerone (MDPV), mephedrone, and methylone.
How to buy K2 spice
Many young people are to K2 spice spray because they falsely think it is safer than marijuana — or that using it would not get them in trouble because it is legal. The reason is that k2 spice does not show up on most drug tests, it is an excellent option for individuals who are concerned about being caught.
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Use of synthetic cannabinoids is alarmingly high, especially among young people. According to the 2012 Monitoring the Future survey of youth drug-use trends, one in nine 12th graders in America reported using synthetic cannabinoids in the past year. This rate, unchanged from 2011, puts synthetic cannabinoids as the second most frequently used illegal drug among high school seniors after marijuana (see chart).
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